Which Brand is the Best: Ancestral Supplements vs Heart and Soil vs Perfect Supplements
There’s no argument— the easiest way to include organ meats into your diet is through high-quality supplements. But with so many big names in the field, it can be hard to know which is the best.
This post compares 3 of the top brands and comes out with my ultimate recommendation of which one is best for overall value.
Every few years, there are new health trends and fads that seem to gain a lot of traction. Lately, that has seemed to ring true for carnivore, ancestral eating, prometabolic, and even paleo-style eating. Within these trending dietary recommendations, there is both a lot of sound advice and also a lot that resembles diet culture.
I’ve talked about supplementing organ meats for years on this blog—and I am always getting asked: Which is the best? There are so many out there that it can feel overwhelming! Two brands that often get a lot of media attention (thanks in part to wellness influencers) are Ancestral Supplements and Heart & Soil, but another worthy contender that deserves mention is Perfect Supplements—a brand known for its commitment to transparency, clean ingredients, and affordability.
These brands focus on delivering the vital nutrients found in beef organ supplements—foods that were a staple of our early ancestors and remain some of the most nutrient-rich foods available. But how do these two brands stack up when comparing testing standards, sourcing qualifications, and ingredient quality?
After trying both, I’m sharing my honest thoughts and preferences… plus which one I’d actually recommend 👀
Health Benefits of Animal Products for Nutrition
I’m a big believer that our overall health begins with food. While I encourage eating as many whole foods as possible, the reality is that our modern world has left much of our food supply depleted. Factors like industrial farming, soil degradation, and monocropping have reduced the amount of essential nutrients found in even the healthiest diets.
That means that even those eating clean, animal foods, and vegetables may still miss key components for immune health, reproductive health, hormone production, and cardiovascular health. This is where nutrient-dense organs—and by extension, organ meat supplements—can fill an important gap.
Organs like beef liver, heart, and bone marrow were once considered sacred by early ancestral healers and traditional peoples, prized for their ability to support immune response, thyroid function, sexual health, and blood flow. These organs contain compounds like glutathione peroxidase, thioredoxin reductase, and iodothyronine deiodinases—all of which play critical roles in antioxidant defense, detoxification, and formation of sex hormones.
In simpler words, they are really amazing sources of nutrients that our bodies can readily use!
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The Brands: Ancestral Supplements vs. Heart & Soil vs Perfect Supplements
Both Ancestral Supplements and Heart & Soil are pioneers in the animal-based diet space, bringing pure nose-to-tail nourishment to consumers who might not have the time—or the stomach—for actual organ meats.
Perfect Supplements, meanwhile, offers a slightly different angle: they focus on single-ingredient, certified-organic products like their Perfect Desiccated Liver, which appeals to those seeking a clean, budget-friendly option with verified third-party testing and USDA organic certification.
Each company offers multi-organ supplements or single-organ formulas featuring beef liver, heart, kidney, spleen, and bone marrow, all freeze-dried in a super bioavailable form. (Bioavailability is just a fancy term for how well your body can use the nutrients you take in)
But while their philosophies overlap, their product quality, third-party testing, and transparency vary in a few key ways. Over the years, I have done the occasional deep dive on supplements, wellness trends, or dietary recommendations-- not only to satisfy my own wellness questions, but to give recommendations to my wellness clients that I am confident in. This is one of 'em!
Ingredient Quality & Sourcing
Ancestral Supplements
Ancestral Supplements sources its organs from grass-fed animals in New Zealand and Australia—regions celebrated for their clean environment and sustainable grazing practices. Each dietary supplement is made with non-defatted organs that preserve natural fats, vitamin B, and amino acids that contribute to energy levels and overall immune function.
Their gelatin capsules contain only freeze-dried organs—no fillers or flow agents.
Heart & Soil
Heart & Soil, founded by Dr. Paul Saladino (author of The Carnivore Code), sources from grass-fed, grass-finished, regeneratively raised cattle. Their mission revolves around ancestral nutrition and “like-supports-like nutrition”—the idea that consuming organ meats from a healthy animal supports the corresponding organ system in the human body (for example, liver supporting detox, or heart supporting circulation).
Heart & Soil’s soil supplements are also freeze-dried and encapsulated in gelatin capsules, ensuring nutrient preservation and maximum absorption.
Perfect Supplements
Perfect Supplements stands out for its simplicity and certifications. Their Perfect Desiccated Liver is made from 100% grass-fed, pasture-raised Argentinian cattle, certified USDA organic, and non-defatted. Unlike some competitors, Perfect Supplements publicly provides independent lab results verifying purity and heavy metal safety.
They also focus on transparency—sharing Drug Administration-compliant labeling and testing data—and are one of the only organ supplement brands verified by third-party testing for both nutrient content and contaminants.
Verdict: All three brands use high-quality, grass-fed sourcing, but Perfect Supplements wins for USDA organic certification and affordability, while Heart & Soil earns points for regenerative farming practices.
Testing, Transparency, and Certification
Ancestral Supplements
Ancestral Supplements conducts third-party testing for safety and purity, claiming compliance with Drug Administration and GMP (Good Manufacturing Practice) standards in the United States. Their formulas are made in FDA-registered facilities that uphold the gold standard of supplement manufacturing.
However, they don’t consistently share full Certificates of Analysis (COAs) publicly. In 2025, the FDA sent a notice to the company about claims on their thyroid product. To clarify, it wasn’t about contamination or safety—it was a regulatory labeling issue related to product claims.
Heart & Soil
Heart & Soil stands out with transparency. Every batch undergoes composite tests through independent labs and the globally recognized substance testing certification program, Informed Sport, which ensures the quality assurance of sports nutrition products. This certification verifies purity and absence of banned substances, making these organ supplements safe for athletes and professionals alike.
They also share batch-level COAs right on their product pages, detailing heavy metals, microbes, and other purity information.
Perfect Supplements
Perfect Supplements also excels here, performing independent lab testing for every batch. They make COAs easily accessible and highlight compliance with GMP and FDA manufacturing standards. Their liver supplement passes tests for heavy metals, pathogens, and pesticide residues, meeting the highest quality standards.
Verdict:
Heart & Soil leads for athlete-safe transparency, but Perfect Supplements provides the clearest purity information and most accessible COAs for consumers.
Health Benefits and Nutritional Value
Each brand delivers essential nutrients that support immune system, thyroid function, bone health, energy levels, menstrual function, and hormonal balance.
Ancestral Supplements offers variety for specific organ systems—like thyroid, adrenal, and heart.
Heart & Soil tailors formulas for cognitive, hormone, and metabolic support.
Perfect Supplements focuses on a single-source beef liver supplement that’s nutrient-rich, affordable, and great for those seeking red blood cell formation and immune function support.
All three deliver pure nose-to-tail nourishment in a super bioavailable form, giving the health benefits of nutrient-dense organs without needing to cook them yourself.
Manufacturing Standards & Consumer Confidence
All brands follow cGMP compliance under the Drug Administration’s regulations. Still, Heart & Soil shines in its quality assurance through independent verification and Informed Sport credentials, which require adherence to the highest quality standards of manufacturing.
That said, Ancestral Supplements remains an organ supplement veteran in the industry, respected for its simplicity, reliability, and long-standing reputation in the United States and abroad.
Pricing, Discounts & Value
Verdict: If you’re budget-conscious or new to organ supplements, Perfect Supplements offers unbeatable quality for the price.
My Experience & Final Thoughts
After personally taking all three brands over the past year, Perfect Supplements, Ancestral Supplements and Heart & Soil, I noticed similar results: steady energy levels, improved immune health, and better overall well-being with all of them. Each brand delivers pure nose-to-tail nourishment in a super bioavailable form, and both make getting your nutritional needs met far easier than cooking organ meats daily.
However, for myself and my family, Perfect Supplements is my top choice. The price cannot be beat-- plus it is a brand that has consistently produced high-quality products. (My husband and I have used their collagen nearly every single day for the last 4+ years). I have confidently recommended their other products since the very start of this business, and I have never been disappointed!
You can save 10% off any of your Perfect Supplement orders with code KAELYN10 ✨
Depending on your own personal wellness goals and budget, any of them are a good choice to help support and boost your nutrient intake. You can shop through the Heart and Soil Amazon storefront HERE, or the Ancestral Supplement storefront HERE.
If you have any questions about any of them, let me know in the comments below!
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A deep dive into 3 of the most popular brands for organ supplements— and which one comes out on top!